Hitung Neutrophil-to-Lymphocyte Ratio (NLR), Monocyte-to-Lymphocyte Ratio (MLR), dan Platelet-to-Lymphocyte Ratio (PLR)

Intruksi

Digunakan sebagai alat bantu menghitung rasio hematologi Neutrophil-to-Lymphocyte Ratio (NLR), Monocyte-to-Lymphocyte Ratio (MLR), dan Platelet-to-Lymphocyte Ratio (PLR) dengan penghitungan menggunakan nilai absolut (dalam satuan ×10⁹/L) atau persentase (%).

Lymphocyte Count:

Required.

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Total WBC Count:

Required for % values.

×10⁹/L

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Neutrophil Count:

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Monocyte Count:

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Platelet Count:

×10⁹/L

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Hasil:

NLR:

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MLR:

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PLR:

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• Keterangan

Neutrophil-to-Lymphocyte Ratio (NLR), Monocyte-to-Lymphocyte Ratio (MLR), dan Platelet-to-Lymphocyte Ratio (PLR) adalah penanda hematologi yang diperoleh dari tes darah rutin, yang sering digunakan sebagai indikator prognosis dalam berbagai kondisi medis, termasuk kanker dan penyakit kardiovaskular. Rasio ini dihitung dengan membagi jumlah satu jenis sel darah dengan jumlah limfosit, yang memberikan wawasan tentang status peradangan dan kekebalan tubuh.

Nilai Normal:

• Lymphocyte Count (Jumlah Limfosit), rentang normal: 1.0–3.0 ×10⁹/L atau 20–40%.
• Neutrophil Count (Jumlah Neutrofil), entang normal: 2.0–7.0 ×10⁹/L atau 40–80%.
• Monocyte Count (Jumlah Monosit), rentang normal:0.2–1.0 ×10⁹/L atau 2–10%.
• Platelet Count (Jumlah Trombosit), rentang normal: 150–450 ×10⁹/L.

Penghitungan Otomatis Rasio Hematologi:
NLR: $$ \text{NLR} = \frac{\text{Jumlah Neutrofil}}{\text{Jumlah Limfosit}} $$ Menunjukkan peradangan sistemik dan respons imun. Kisaran normal: 1–3. MLR: $$ \text{MLR} = \frac{\text{Jumlah Monosit}}{\text{Jumlah Limfosit}} $$ Digunakan sebagai penanda peradangan kronis atau keganasan tertentu. Kisaran normal: 0,1–0,3. PLR (Rasio Trombosit-ke-Limfosit): $$ \text{PLR} = \frac{\text{Jumlah Trombosit}}{\text{Jumlah Limfosit}} $$ Terkait dengan kondisi peradangan dan risiko kardiovaskular. Kisaran normal: 100–300.

Literatur

Djordjevic, D., Rondovic, G., Surbatovic, M., Stanojevic, I., Udovicic, I., Andjelic, T., Zeba, S., Milosavljevic, S., Stankovic, N., Abazovic, D., Jevdjic, J., & Vojvodic, D. (2018). Neutrophil-to-Lymphocyte Ratio, Monocyte-to-Lymphocyte Ratio, Platelet-to-Lymphocyte Ratio, and Mean Platelet Volume-to-Platelet Count Ratio as Biomarkers in Critically Ill and Injured Patients: Which Ratio to Choose to Predict Outcome and Nature of Bacteremia?. Mediators of inflammation, 2018, 3758068. https://doi.org/10.1155/2018/3758068

Zahorec, R. (2001). Ratio of neutrophil to lymphocyte counts—Rapid and simple parameter of systemic inflammation and stress in critically ill patients. Bratislava Medical Journal, 102(1), 5–14. https://pubmed.ncbi.nlm.nih.gov/11723675/

Faria, S. S., Fernandes, P. C., Jr., Silva, M. J., et al. (2016). The neutrophil-to-lymphocyte ratio: A narrative review on its utility in clinical practice and prognosis in various diseases. Critical Reviews in Clinical Laboratory Sciences, 53(5), 302–310. https://doi.org/10.3332/ecancer.2016.702

Templeton, A. J., McNamara, M. G., Šeruga, B., et al. (2014). Prognostic role of platelet to lymphocyte ratio in solid tumors: A systematic review and meta-analysis. Cancer Epidemiology Biomarkers & Prevention*, 23(7), 1204–1212. https://pubmed.ncbi.nlm.nih.gov/24793958/

Forget, P., Khalifa, C., Defour, J.-P., Latinne, D., Van Pel, M.-C., & De Kock, M. (2017). What is the normal value of the neutrophil-to-lymphocyte ratio? BMC Research Notes, 10(1), Article No:12. https://doi.org/10.1186/s13104-016-2335-5